December 7, 2022

We Have All GLP-1s Now!

We began prescribing Mounjaro (the newest GLP-1 analog) at Cordova Weight Loss with great results! It is a remarkably good weight loss medication. Due to patient interest, we also now prescribe the other GLP-1 drugs which are Victoza, Saxenda, Trulicity, Ozempic, and Wegovy. Some people may want to try the earlier drugs for insurance coverage or other reasons. These can be taken with Phentermine as well.

Below is a timeline describing all the GLP-1 drugs and how they compare to one another.

GLP 1 Drugs Timeline 12 16 in

The first GLP-1 analog was Victoza (liraglutide), brought out in 2010. Then Saxenda (also liraglutide) came out in 2014. It's the same drug as Victoza, but in a higher dose. These two injections were used daily, because at that time they had not discovered how to extend the life of the drug in your body.

Trulicity (dulaglutide) debuted in 2014, with a much longer half-life, so it only needed to be injected once per week, instead of everyday. It also provided better weight loss than the earlier meds.

In 2017, Ozempic (semaglutide) came out and it was followed in 2021 by Wegovy (also semaglutide), which is the same GLP-1 but in a higher dose. These provided even better weight loss than previous GLP-1 drugs. They are also used once a week, by injection.

Mounjaro (tirzepatide) came out in May of 2022, and it caused about 50% better weight loss than Ozempic and Wegovy (both semaglutide). Mounjaro is also taken once a week by injection.

Initial Results on Mounjaro

We have been prescribing Mounjaro long enough to see a few patients back for refills. Most are experiencing little or no side effects. This is not a scientific study, but here are the results of pounds lost on our first 17 Mounjaro patients:

Initial monjaro results 17 patients

The average weight loss was 10 lbs. Most of these patients will increase from 2.5mg weekly to 5mg weekly, but a few elected to stay on the 2.5mg dosage because it's working well enough. Mounjaro can be escalated every four weeks by 2.5mg, if needed, to a maximum of 15mg. These are pretty impressive results on just the starting dose!

If you'd like to try one of these meds, come in and see us at Cordova Weight Loss!

Written by: Dr. John Bills Jr and JoAnna Lagownik